NFL Week 4 Predictions: Latest Spread from Kalshi and Polymarket

Week 4 begins Thursday, Oct. 1, with Steelers (58%) at Browns (43%), each 2-1 after Sunday victories. The Colts (64%) and Commanders (37%) kick off Sunday in London at 9:30 a.m. ET following their first wins of the season.

The Lions (65%) go to the Panthers (36%) on Sunday night time, whereas the Falcons (42%) go to the Saints (59%) to shut the week Monday night time. Below are Week 4 odds and predictions instantly from Kalshi and Polymarket US.

NFL week 4 odds: Compare strains and totals for each sport up to date each day

Week 4 odds, unfold and moneyline at Kalshi

Pittsburgh Steelers @ Cleveland Browns | Thursday, Oct. 1 | 8:15 p.m. ET | Prime Video | Huntington Bank Field, Cleveland, OH |

Pittsburgh’s 30-27 win over Cincinnati and Cleveland’s 21-18 victory in opposition to Carolina put each AFC North rivals at 2-1 coming into Thursday. Aaron Rodgers threw three landing passes for the Steelers. The Pittsburgh protection sealed the win with a late strip-sack and restoration. Cleveland’s defensive entrance pressured Bryce Young all through its win, with Deshaun Watson connecting with Harold Fannin Jr. for the game-winning rating with beneath two minutes to go.

Indianapolis Colts @ Washington Commanders | Sunday, Oct. 4 | 9:30 a.m. ET | NFL Network | Tottenham Hotspur Stadium, London |

Indianapolis and Washington every earned their first win Sunday, leaving each at 1-2 earlier than their London assembly. The Colts beat Houston 19-17 on a late discipline objective, whereas the Commanders edged Seattle 33-31 with Marcus Mariota beginning rather than Jayden Daniels. Washington’s Week 4 quarterback state of affairs stays value watching, as Daniels is predicted to overlook 2-4 weeks.

Arizona Cardinals @ New York Giants | Sunday, Oct. 4 | 1 p.m. ET | CBS | MetLife Stadium, East Rutherford, NJ |

Arizona misplaced 36-30 at San Francisco, whereas the Giants beat Tennessee 12-7 to maneuver to 2-1. New York received with Jameis Winston beginning following the season-ending harm to Jaxson Dart. The Cardinals have dropped two straight since upsetting the Chargers of their opener. In early-week pricing, that is the tightest Week 4 sport on the board.

Dallas Cowboys @ Houston Texans | Sunday, Oct. 4 | 1 p.m. ET | FOX | Reliant Stadium, Houston, TX |

Dallas fell 34-31 to Baltimore in Brazil, and Houston misplaced 19-17 at Indianapolis after surrendering the lead late. The Cowboys are 1-2, whereas the Texans fell to 0-3 after one other slim defeat. Dallas is averaging 29.3 factors per sport and giving up 27.3 per contest. Houston has scored a median of 18.0 by way of three video games and surrendered 25.0.

Green Bay Packers @ Tampa Bay Buccaneers | Sunday, Oct. 4 | 1 p.m. ET | FOX | Raymond James Stadium, Tampa, FL |

Green Bay misplaced 35-14 to Atlanta on Thursday, and Tampa Bay fell 23-16 to Minnesota on Sunday. The Packers enter at 1-2, whereas the Buccaneers are 0-3 after Minnesota sacked Baker Mayfield six occasions. Mayfield exited late with a hand harm. He’s scheduled for an MRI on a dislocated proper thumb to find out the extent of the injury.

(*4*) | Sunday, Oct. 4 | 1 p.m. ET | CBS | Paycor Stadium, Cincinnati, OH |

Jacksonville routed New England 35-6 to maneuver to 2-1, with Trevor Lawrence throwing three landing passes. Cincinnati slipped to 2-1 after a 30-27 loss in Pittsburgh, regardless of its offense maintaining tempo till the Steelers’ late strip-sack. The Bengals are a slim residence favourite in early buying and selling.

Los Angeles Rams @ Philadelphia Eagles | Sunday, Oct. 4 | 1 p.m. ET | FOX | Lincoln Financial Field, Philadelphia, PA |

The Rams misplaced 30-26 at Denver after main 16-0 at halftime and enter Week 4 at 1-2. Philadelphia fell 27-7 at Chicago on Monday to drop to 2-1, turning the ball over 3 times and gaining simply 52 internet yards after halftime. Los Angeles is now a firmer street favourite at 61%, whereas the Eagles want a response from Jalen Hurts and their offense.

New England Patriots @ Buffalo Bills | Sunday, Oct. 4 | 1 p.m. ET | CBS | Highmark Stadium, Orchard Park, NY |

Buffalo beat the Chargers 24-16 regardless of committing 5 turnovers and improved to 3-0. New England fell 35-6 at Jacksonville and sits at 1-2. The undefeated Bills are closely favored at residence, whereas the Patriots hit the street trying to find solutions after an uneven begin to the season.

New York Jets @ Chicago Bears | Sunday, Oct. 4 | 1 p.m. ET | FOX | Soldier Field, Chicago, IL |

The Jets misplaced 31-24 at Detroit and enter Week 4 at 1-2. Chicago beat Philadelphia 27-7 on Monday behind two landing passes and a speeding rating from Case Keenum, plus three defensive takeaways. Chicago is 2-1 and favored at residence, although Caleb Williams’ hamstring harm leaves its Week 4 quarterback image value monitoring.

Tennessee Titans @ Baltimore Ravens | Sunday, Oct. 4 | 1 p.m. ET | CBS | M&T Bank Stadium, Baltimore, MD |

Tennessee misplaced 12-7 on the Giants and is 0-3, whereas Baltimore beat Dallas 34-31 in Brazil on Tyler Loop’s 56-yard late discipline objective to succeed in 2-1. The Titans struggled to complete drives in opposition to New York, however did handle to return from behind and maintain the sport fascinating late. Baltimore’s win over the Cowboys got here on the heels of a blown fourth quarter lead at residence to the Saints.

Miami Dolphins @ Minnesota Vikings | Sunday, Oct. 4 | 4:05 p.m. ET | FOX | U.S. Bank Stadium, Minneapolis, MN |

Miami misplaced 24-10 at residence to Kansas City to fall to 0-3. Minnesota beat Tampa Bay 23-16 to enhance to 3-0, leaning on a protection that sacked Baker Mayfield six occasions and pissed off the Buccaneers. Through three video games, the Dolphins are final within the league in level differential at -50.

Denver Broncos @ San Francisco 49ers | Sunday, Oct. 4 | 4:25 p.m. ET | CBS | Levi’s Stadium, Santa Clara, CA |

Denver erased a 16-0 halftime deficit to beat the Rams 30-26, whereas San Francisco held off Arizona 36-30 behind 4 Brock Purdy landing passes. Bo Nix threw for 2 scores and ran for one more because the Broncos managed the second half. The Denver protection pitched in on the scoreboard by way of a 66-yard choose six from Talanoa Hufanga.

Kansas City Chiefs @ Las Vegas Raiders | Sunday, Oct. 4 | 4:25 p.m. ET | CBS | Allegiant Stadium, Las Vegas, NV |

Kansas City beat Miami 24-10, and Las Vegas received 35-27 at New Orleans, leaving each AFC West rivals at 3-0. The Raiders pressured 4 fourth-quarter takeaways in opposition to the Saints, whereas Patrick Mahomes threw two landing passes within the Chiefs’ win. Sunday’s divisional assembly will settle early management of the division, and cut back the variety of undefeated groups by one.

Los Angeles Chargers @ Seattle Seahawks | Sunday, Oct. 4 | 4:25 p.m. ET | CBS | Lumen Field, Seattle, WA |

The Chargers fell 24-16 at Buffalo and are 0-3. Seattle misplaced 33-31 at Washington regardless of 4 Sam Darnold landing passes, two to Jaxon Smith-Njigba, dropping the Seahawks to 2-1. Los Angeles entered the season seen as an AFC West contender, however is now trying to find solutions and seeking to snap a three-game skid.

Detroit Lions @ Carolina Panthers | Sunday, Oct. 4 | 8:20 p.m. ET | NBC | Bank of America Stadium, Charlotte, NC |

Detroit beat the Jets 31-24 behind three second-half Jahmyr Gibbs touchdowns, together with the successful reception. Carolina misplaced 21-18 at Cleveland after its offense struggled in opposition to the Browns’ defensive stress. The Lions are 2-1 and the Panthers 1-2 coming into Sunday night time, with market pricing leaning towards the street aspect.

Atlanta Falcons @ New Orleans Saints | Monday, Oct. 5 | 8:15 p.m. ET | ESPN | Caesars Superdome, New Orleans, LA |

Atlanta routed Green Bay 35-14 on Thursday, with Bijan Robinson speeding for 194 yards and two touchdowns to elevate the Falcons to 1-2. New Orleans fell 35-27 to Las Vegas after 4 fourth-quarter turnovers and can also be 1-2. When the NFC South rivals meet Monday night time, the winner might take the early lead within the division chase, pending outcomes from different video games.

Notable Week 4 line strikes

Green Bay has climbed from 52% to 64% in opposition to Tampa Bay, the largest Week 4 transfer for the reason that first Sept. 22 snapshot. Miami fell from 28% to 17% at Minnesota, whereas Detroit rose from 55% to 65% at Carolina.

The Rams have climbed from 52% to 61% at Philadelphia, whereas Chicago is up from 58% to 63% in opposition to the Jets. Arizona moved from 48% to 53% on the Giants, Denver rose from 37% to 43% in opposition to San Francisco, and Dallas slipped from 50% to 44% at Houston.

NFL futures market outlook

With Week 3 full, Buffalo leads the Kalshi 2027 Super Bowl winner market at 12.5%, adopted by the Rams at 11.5% and San Francisco at 9.5%.

Behind the leaders, Baltimore and Kansas City are at 7.5%, with Seattle at 6.5%. Since Sept. 22, Buffalo rose from 11.5% to 12.5%, whereas the Rams slipped from 12.5% to 11.5%.

Josh Allen leads the Kalshi 2026-27 NFL MVP market at 25.5%. Through three video games, Allen has thrown for 5 scores and rushed for one more six as Buffalo opens the season at 3-0.

Brock Purdy has moved into second place at 18.5%. Rounding out the highest 5 are Lamar Jackson at 11.5%, Joe Burrow at 8.5%, and Patrick Mahomes at 7.5%. Allen was at 27.5% on Sept. 22, whereas Purdy was at 9.5%.

Readers can compare prediction market apps and assessment current NFL promos earlier than selecting the place to commerce Week 4 and season-long contracts. You may print a Week 4 pick-em sheet.